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What are the Side Effects of the FERINJECT Treatment?

Published in Iron Deficiency Treatment 3 mins read

FERINJECT (ferric carboxymaltose) treatment, while effective for iron deficiency, can lead to various side effects ranging from common and mild to rare and serious, including severe allergic reactions.

Understanding FERINJECT Side Effects

FERINJECT is an intravenous iron therapy, and like all medications, it carries a risk of side effects. It's crucial for patients to be aware of these potential reactions and report any concerns to their healthcare provider.

Serious Allergic Reactions and Other Severe Effects

One of the most critical concerns with FERINJECT treatment is the potential for serious allergic reactions, which can be life-threatening. These reactions may manifest as:

  • Nausea and Vomiting
  • Difficulty breathing
  • Shock
  • Loss of consciousness or collapse
  • Low blood pressure

Due to the risk of such severe reactions, medical professionals typically monitor patients closely for signs and symptoms of allergic reactions during and for at least 30 minutes following the administration of FERINJECT.

Common Side Effects

Many individuals experience mild to moderate side effects that are generally manageable. These can include:

  • Headache: Often mild and resolves on its own.
  • Dizziness: May occur shortly after infusion.
  • Nausea: Can be mild and temporary.
  • Injection Site Reactions: Pain, bruising, or discolouration (browning of the skin) at the site of injection, which can be persistent.
  • Flushing: A sensation of warmth or redness of the skin.
  • Changes in Taste: A metallic taste in the mouth.
  • Joint and Muscle Pain: Aches in joints or muscles.
  • Rash: Skin irritation or eruption.

Less Common Side Effects

Some other side effects that might occur less frequently include:

  • Vomiting
  • Abdominal pain
  • Diarrhea or constipation
  • Chills and fever
  • Itching
  • Temporary increases in liver enzymes

Table of Potential FERINJECT Side Effects

Category Common Side Effects Less Common Side Effects Serious/Rare Side Effects
General Headache, Dizziness, Nausea, Flushing, Metallic taste Vomiting, Abdominal pain, Chills, Fever, Itching Serious allergic reactions (Anaphylaxis), Shock, Collapse
Injection Site Pain, Bruising, Discoloration (brown staining) Swelling
Body Systems Joint/Muscle pain, Rash Diarrhea, Constipation, Elevated liver enzymes Low blood pressure, Difficulty breathing, Loss of consciousness
Metabolic Hypophosphatemia (low phosphate levels in the blood)

What to Do If You Experience Side Effects

  • Immediate Serious Reactions: If you experience any signs of a severe allergic reaction (e.g., breathing difficulties, severe dizziness, collapse), it is a medical emergency. Alert your healthcare provider immediately during or after the infusion.
  • Common or Mild Reactions: For less severe side effects, inform your doctor or nurse. They can provide advice on how to manage them or assess if further action is needed. Do not hesitate to discuss any discomfort or unusual symptoms you experience.
  • Persistent Discoloration: If you notice persistent brown staining at the injection site, discuss this with your doctor. While often harmless, it can be a cosmetic concern.

Important Considerations

It's important to have an open conversation with your doctor about your medical history, including any allergies or sensitivities, before starting FERINJECT treatment. Your doctor will weigh the benefits against the potential risks to determine if FERINJECT is the appropriate treatment for you. For detailed information, always refer to the official FERINJECT Patient Information Leaflet or consult your healthcare professional.